1Alyaa Kadhim Mohammed, 2Ban Al-Drobie PhD, and 3Bashar H. Abdullah PhD,
1Department of Oral and Maxillofacial Pathology, College of Dentistry, University of Baghdad, Baghdad, Iraq.2Department of Oral and Maxillofacial Pathology, College of Dentistry, University of Baghdad, Baghdad, Iraq. ³Department of Oral and Maxillofacial Pathology, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Corresponding author:Alyaa Kadhim Mohammed
Received 23 September 2022.
Accepted for publication on Novmber 10, 2022.
Published Feburary 19, 2023.
Background Salivary gland tumors account for about 6% of all head and neck cancers. Salivary gland carcinomas (SGCs) are uncommon cancers with a wide morphological range and variable clinical behavior. Objectives The study’s goal was to examine the demographic description of SGCs patients in the head and neck region. Materials and Methods A retrospective review of ninety-three formalin-fixed, paraffin-embedded tissue blocks reported as SGCs of the head and neck region (37 cases of MEC, 44 cases of AdCC, and 12 cases of PAC) were retrieved from the archives of Oral & Maxillofacial Pathology/University of Baghdad and Ghazi Al-Harerri Hospital-Medical City, from 1972 to 2021. The diagnosis of each case was confirmed by the Haematoxylin and Eosin stained sections by two expert pathologists and according to the grading system of the AFIP for MEC and Perzin/Szanto for AdCC. Results Patients with SGCs ranged in age from 7 to 71 years old, with a mean of (46.05±14.20). According to the histological subtypes, the highest cases are in AdCC and MEC, accounting for 44 (47.3%) and 37(39.8%), respectively, and the highest recorded cases were in «Maxillary mass, accounted for 24 (25.8%). According to the grading system of MEC, there was a highly significant difference at P<0.01. On the other hand, according to the histological pattern of AdCC there was a highly significant difference at P<0.01. Conclusion These results suggest that AdCC and MEC types were the most prevalent salivary gland carcinomas in the head and neck region, and the maxillary mass was the most predominant site. Also, the cribriform pattern of AdCC was the predominant histological pattern, which means grade II of AdCC was the predominant as a result of this study.